Larry Heisenberg had the benefit of a childhood in the inner city slums of Boston, an early education in a public school designated amongst the worst in America and an adolescence spent working in mind-numbing warehouses and factories. As a motorcycle enthusiast, he learned about orthopedic surgery and the neurologic management of comatose patients the old-fashioned way, by being the patient. His penchant for dangerous women and his familiarity with ethically-neutered men took him to places and situations depicted in The Jakes Protocol. The story is part biography and part fiction. It will resonate with readers who have led reckless lives similar to Heisenberg’s own because they will recognize it as not only plausible but also factual. Heisenberg’s struggles, conquests, insights and uncertainties form the web upon which this murder mystery is woven.